Why the study?
Does the GenMark Diagnostics eSensor RVP cross-react with EV-D68, and can signal intensity differentiate it from HRV in respiratory samples?
Population
62 consecutive de-identified nasopharyngeal swab samples submitted to the clinical microbiology laboratory…
Comparison
GenMark Diagnostics eSensor respiratory viral… vs Traditional PCR amplification of the…
Design
Other, GenMark eSensor RVP results were masked during PCR and sequencing…
Authors
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May support EV-D68 differentiation from HRV via eSensor RVP cut-off; leaves open prospective clinical validation.
Does the GenMark Diagnostics eSensor RVP cross-react with EV-D68, and can signal intensity differentiate it from HRV in respiratory samples?
The GenMark Diagnostics eSensor RVP platform cross-reacts with EV-D68, but a signal intensity cut-off of 40 nA can accurately differentiate EV-D68 from HRV.
McAllister et al. (2015) studied this question.
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