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March 17, 2025ESC Heart FailureOpen Access

Risk Classification for Long-Term Mortality Among Patients with Acute Heart Failure: China PEACE 4YMortality

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Why the study?

Tools to predict long-term mortality among patients hospitalized with acute heart failure in China are limited.

Does a 13-predictor risk model accurately predict 4-year mortality in patients hospitalized with acute heart failure and discharged alive?

Population

4875 patients hospitalized for AHF and discharged alive

Design

Prospective cohort study

Follow-up

4 years

Key result

A 13-predictor model demonstrated reasonable discrimination for predicting 4-year mortality in patients discharged alive after acute heart failure (development C-index 0.726; 95% CI 0.714-0.739).

Authors

WWWei WangLZLihua ZhangGHGuangda He

Discussion

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Member takes

Overview

May aid post-AHF discharge prognostication; leaves open external validation before clinical adoption.

Study Design

Type

Cohort (n=4,875)

Multicenter

Yes

Structured PICO

Does a 13-predictor risk model accurately predict 4-year mortality in patients hospitalized with acute heart failure and discharged alive?

P
Population
4875 patients hospitalized for acute heart failure (AHF) and discharged alive in China
I
Intervention
13-predictor risk model (including age, medical history of hypertension, COPD, HF, systolic blood pressure, BUN, albumin, hs-TnT, NT-proBNP, serum creatine, KCCQ-12 score, and LVEF)
O
Outcome
4-year mortalityhard clinical

Main Result

Effect estimate: C-index 0.726 (95% CI 0.714-0.739)

A novel 13-variable risk score provides reasonable discrimination for predicting 4-year mortality in Chinese patients discharged alive after acute heart failure.

Cite This Study

Wang et al. (2025) conducted a cohort in Acute heart failure (n=4,875). 13-predictor risk model was evaluated on 4-year mortality (C-index 0.726, 95% CI 0.714-0.739). A 13-predictor model demonstrated reasonable discrimination for predicting 4-year mortality in patients discharged alive after acute heart failure (development C-index 0.726; 95% CI 0.714-0.739).

synapsesocial.com/papers/6a0fa2032badbc352afe756ahttps://doi.org/10.1002/ehf2.15207
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