Key result
GWTG-HF score predicts 4-week mortality in ADHF, reaching ~56% in the highest score group.
Why the study?
The study was conducted to evaluate the GWTG-HF score for predicting 4-week mortality in acute decompensated heart failure patients of South East Asian ethnicity, comparing it with the APACHE 2 score and NT-proBNP.
Does the GWTG-HF score predict 4-week mortality and correlate with NT-proBNP levels compared to the APACHE 2 score in South East Asian patients with acute decompensated heart failure?
Observational (n=300)
No
Does the GWTG-HF score predict 4-week mortality and correlate with NT-proBNP levels compared to the APACHE 2 score in South East Asian patients with acute decompensated heart failure?
Effect estimate: R=0.34
p-value: p=<0.00001
The GWTG-HF score is an easily calculated bedside tool that predicts 4-week mortality and correlates with NT-proBNP in South East Asian patients with ADHF, though APACHE 2 performs better for mortality prediction.
May support short-term risk stratification in ADHF; hypothesis-generating in Southeast Asian cohorts, needs prospective validation.
Objectives To study Get with the guidelines heart failure Score (GWTG-HF) among patients of acute decompensated heart failure, correlate it with outcome of survival or death till 4 week of illness, compare its performance with APACHE 2 score and to Compare its results with NT PROBNP in predicting mortality amongst patient of south east Asian ethnicity. Study design prospective observational study at medical wards and ICUs in the Department of Cardiology, SMS medical college. Methods In this study 300 patients of acute decompensated heart failure, as per Framingham criteria were analyzed and each patient underwent a complete clinical evaluation along with calculation of GWTG HF and APACHE 2 score. All the patients had NT pro BNP test within 48 hours of admission. Patient were then followed till 4 weeks of illness for outcome of survival or death, whichever occurred earlier. GWTG HF score of the patient was then compared with APACHE 2 score and it was correlated with the outcome of patients and NT pro BNP levels. Results The GWTG-HF score could predict the outcome of survival and death in ADHF patients of south east Asian ethnicity. When compared, APACHE 2 score performed better than GWTG-HF score in predicting outcome. However, GWTG-HF score was easily calculated at the bedside and was easy to use. GWTG-HF score correlated with NT-pro BNP levels with rising score having higher NT pro BNP levels.
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Kumar et al. (2023) conducted an observational in Acute decompensated heart failure (n=300). Get with the Guidelines Heart Failure (GWTG-HF) Score vs. APACHE 2 Score was evaluated on 4-week mortality (R=0.34, p=<0.00001). The GWTG-HF score significantly predicted 4-week mortality in patients with acute decompensated heart failure (R=0.34, p<0.00001), with mortality rates increasing progressively from 0% to 55.56% across higher score groups.
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