Predicting Left Ventricular Dysfunction after Surgery in Patients with Chronic Mitral Regurgitation: Assessment of Myocardial Deformation by 2-Dimensional Multilayer Speckle Tracking Echocardiography

43 consecutive patients with chronic severe primary mitral valve regurgitation (MR) with preserved LV systolic function (LVEF >60%, LVESD <40 mm) scheduled for mitral valve replacement (MVR) or MV repair. Mean age 51.7±14.3 years, 58.1% male. Exclusions: secondary MR, other concomitant moderate/severe valvular disease, coronary artery disease, history of myocardial infarction, CABG, acute coronary syndrome, atrial fibrillation, chronic renal failure, or suboptimal imaging.

Preoperative regional left ventricular contractile function assessment using two-dimensional multilayer speckle-tracking echocardiography (2D MSTE), specifically measuring mid-layer global longitudinal strain (GLS).

Postoperative LV remodeling or LV dysfunction (defined as a reduction in LVEF or increase of LVEDD at 3 months compared to baseline).surrogate