Why the study?
Specific respiratory manoeuvres needed for inert gas rebreathing cardiac output measurement might affect pivotal cardiopulmonary exercise test parameters.
Do rebreathing manoeuvres for non-invasive measurement of cardiac output during maximum exercise test alter cardiopulmonary parameters in heart failure patients?
Do rebreathing manoeuvres for non-invasive measurement of cardiac output during maximum exercise test alter cardiopulmonary parameters in heart failure patients?
Inert gas rebreathing manoeuvres during CPET in heart failure patients alter key parameters such as peak workload and VE/VCO2 slope, which must be interpreted with caution.
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Rebreathing during CPET may confound workload and VE/VCO2 slope in HF; hypothesis-generating for protocol standardization before wider adoption.
Vignati et al. (2019) studied this question.
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