Why the study?
Interventions on graft bifurcation lesions are uncommon, especially in the setting of acute coronary syndromes.
Does a tailored percutaneous coronary intervention approach improve outcomes in patients with vein graft bifurcation lesions presenting as acute coronary syndrome?
Does a tailored percutaneous coronary intervention approach improve outcomes in patients with vein graft bifurcation lesions presenting as acute coronary syndrome?
Tailored PCI strategies for complex vein graft bifurcation lesions in the setting of ACS can yield excellent angiographic and long-term clinical outcomes.
Supports feasibility of tailored PCI in vein graft bifurcations; hypothesis-generating and should not change practice without prospective trials.
Interventions on graft bifurcation lesions are uncommon, especially in the setting of acute coronary syndromes (ACS). We described three cases of graft bifurcation intervention where we tailored our approach based on lesion characteristics, anatomy, and angulation to achieve excellent angiographic and clinical outcomes. In case 1, shared ostia of saphenous vein graft (SVG) to Diagonal (D) and Radial graft to Obtuse Marginal (OM) was severely stenosed. We prioritized the radial arterial graft as it is known to have a longer patency rate over a totally occluded SVG of an undetermined period. We performed provisional stenting of the ostium of the radial artery and balloon angioplasty of the SVG ostium, while stenting the body of the SVG. In case 2 (bifurcation lesion at the anastomosis of SVG to D1 and sequential jump graft to OM), we utilized a V stenting strategy after an embolization protection device (EPD) was deployed in the branch with a suitable landing zone. Kissing balloon dilatation of both the branches was performed both pre- and poststenting. In case 3 (bifurcation lesion at SVG to OM and Sequential "T" graft to diagonal), there was >90% angulation between both the grafts. We used "T" stenting strategy in this case. At 2-year follow-up, patients had no major adverse cardiovascular events since and remained symptom free.
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Feghaly et al. (2020) studied this question.
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