Key result
Non-pharmacological interventions like renal denervation and nerve stimulators remain under investigation for HF.
Why the study?
The lack of recent breakthrough medical advances in heart failure has driven the development of non-pharmacological interventions to modulate cardiac autonomic tone.
Do non-pharmacological interventions modulating cardiac autonomic tone improve outcomes in patients with heart failure?
Do non-pharmacological interventions modulating cardiac autonomic tone improve outcomes in patients with heart failure?
This review summarizes emerging non-pharmacological therapies targeting the autonomic nervous system for the treatment of heart failure.
Novel autonomic modulation strategies expand options in heart failure; leaves open their clinical role pending randomized trials.
The autonomic nervous system has a significant role in the pathophysiology and progression of heart failure. The absence of any recent breakthrough advances in the medical therapy of heart failure has led to the evolution of innovative non-pharmacological interventions that can favourably modulate the cardiac autonomic tone. Several new therapeutic modalities that may act at different levels of the autonomic nervous system are being investigated for their role in the treatment of heart failure. The current review examines the role of renal denervation, vagal nerve stimulators, carotid baroreceptors, and spinal cord stimulators in the treatment of heart failure.
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Singh et al. (2013) conducted a review in Heart failure. Non-pharmacological interventions (renal denervation, vagal nerve stimulators, carotid baroreceptors, spinal cord stimulators) was evaluated. Non-pharmacological interventions, including renal denervation, vagal nerve stimulators, carotid baroreceptors, and spinal cord stimulators, are being investigated to treat heart failure.
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