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November 26, 2003New England Journal of MedicineOpen Access

Lp(a) Lipoprotein, Vascular Disease, and Mortality in the Elderly

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Why the study?

Is Lp(a) lipoprotein associated with an increased risk of vascular disease and mortality in older U.S. adults?

Population

older U.S. adults

Design

Cohort

Authors

AAAbraham A. AriyoCTChau ThachRTRussell P. Tracy

Discussion

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Overview

Lp(a) was associated with vascular risk in older adults; extends prior data but leaves open whether measurement should guide care.

Structured PICO

Is Lp(a) lipoprotein associated with an increased risk of vascular disease and mortality in older U.S. adults?

P
Population
older U.S. adults
I
Intervention
Lp(a) lipoprotein levels (exposure)
O
Outcome
vascular disease and mortalityhard clinical

Cite This Study

Ariyo et al. (2003) studied this question.

synapsesocial.com/papers/6a0fcbc15725bbd5cc6019c1https://doi.org/10.1056/nejmoa001066
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Significance of Serum Lipoprotein(a) Concentration in the Elderly with Regard to Vascular Complications and Long-term Prognosis.1999 · 1 citations
  2. 2Comparison of Lipoprotein(a) Levels between Elderly and Middle‐Aged Men with Coronary Artery Disease2007 · 14 citations
  3. 3Elderly patients with very high plasma lipoprotein(a) concentrations and few cardiovascular consequences: a case series2024 · 4 citations
  4. 4All-Cause Mortality and Competing Risks of Fatal and Nonfatal Vascular Events in the Italian Longitudinal Study on Aging: Impact of Lipoprotein(a)2009 · 6 citations
  5. 5Lipoprotein (a) and vascular disease: thrombogenesis and atherogenesis1995 · 30 citations