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March 1, 2000Annual Review of Physiology

Sodium-Calcium Exchange: A Molecular Perspective

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Authors

KPKenneth D. PhilipsonElectrophysiologyDNDebora A. NicollUniversity of California, Los Angeles

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Implication

NCX modulation warrants preclinical exploration in cardiac disease; leaves open clinical translation pending targeted trials.

Key Points

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Cite This Study

Philipson et al. (2000) studied this question.

synapsesocial.com/papers/6a0fcefcfa36b6e053fceddfhttps://doi.org/10.1146/annurev.physiol.62.1.111
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain.1995 · 248 citations
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  3. 3Molecular Cloning and Functional Expression of the Cardiac Sarcolemmal Na + -Ca 2+ Exchanger1990 · 745 citations
  4. 4Expressional analysis of the cardiac Na–Ca exchanger in rat development and senescence1998 · 99 citations
  5. 5Cardiac Na+/Ca2+ exchange activity in patients with end-stage heart failure1996 · 152 citations