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July 1, 2025JACC Case ReportsOpen Access

Transcatheter Tricuspid Valve Replacement After Failed Transcatheter Annuloplasty and Edge-to-Edge Repair

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Key result

EVOQUE TTVR resolves severe TR after failed prior interventions in a case report.

  • n=1

Why the study?

The feasibility of EVOQUE transcatheter tricuspid valve replacement after failed percutaneous tricuspid annuloplasty and edge-to-edge repair had not been reported.

Does transcatheter tricuspid valve replacement improve outcomes in a patient with severe tricuspid regurgitation after failed annuloplasty and edge-to-edge repair?

Population

An 80-year-old man with severe TR after failed annuloplasty and edge-to-edge repair

Comparison

TTVR with a 48-mm EVOQUE valve

Design

Case report

Follow-up

1 month

Authors

Stefan Toggweiler
Stefan ToggweilerInterventional / Structural Cardiology
FMFederico MoccettiUniversity of LucerneSSSimon F. StämpfliCardiac Imaging

Discussion

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Member takes

Implication

May support use after failed tricuspid interventions in select cases; hypothesis-generating for durability and outcomes in prospective studies.

Study Design

Type

Case Report (n=1)

Structured PICO

Does transcatheter tricuspid valve replacement improve outcomes in a patient with severe tricuspid regurgitation after failed annuloplasty and edge-to-edge repair?

P
Population
An 80-year-old man with atrial fibrillation and severe tricuspid regurgitation after failed percutaneous annuloplasty and edge-to-edge repair (n=1).
I
Intervention
Transcatheter tricuspid valve replacement (TTVR) with a 48-mm EVOQUE valve.
O
Outcome
Clinical and echocardiographic outcomes (residual TR, paravalvular leak, NYHA functional class) at 1 month.surrogate

Transcatheter tricuspid valve replacement is a feasible and effective treatment option for severe tricuspid regurgitation even in complex cases with prior failed transcatheter annuloplasty and edge-to-edge repair.

Cite This Study

Toggweiler et al. (2025) conducted a case report in Severe tricuspid regurgitation (n=1). Transcatheter tricuspid valve replacement (TTVR) with EVOQUE valve was evaluated on Residual TR, paravalvular leak, and NYHA functional class. Transcatheter tricuspid valve replacement with the EVOQUE valve successfully treated severe tricuspid regurgitation after failed prior interventions, resulting in no residual TR at 1 month.

synapsesocial.com/papers/6a0fdbdd5725bbd5cc602958https://doi.org/10.1016/j.jaccas.2025.103945

Topics

Tricuspid regurgitation
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transcatheter Versus Medical Treatment of Patients With Symptomatic Severe Tricuspid Regurgitation2019 · 479 citations
  2. 2The need for a new tricuspid regurgitation grading scheme2017 · 572 citations
  3. 3Tricuspid regurgitation is associated with increased mortality independent of pulmonary pressures and right heart failure: a systematic review and meta-analysis2018 · 423 citations
  4. 4Impact of tricuspid regurgitation on long-term survival2004 · 1,702 citations