Key result
Evoque TTVR safely eliminates tricuspid regurgitation after failing heterotopic caval valve implantation.
Why the study?
Long-term durability and management of device failure after heterotopic caval valve implantation for severe tricuspid regurgitation remain poorly defined.
Can orthotopic transcatheter tricuspid valve replacement (TTVR) using the Evoque system safely and effectively treat severe tricuspid regurgitation in a patient with a failing heterotopic caval valve prosthesis?
Case Report (n=1)
No
Can orthotopic transcatheter tricuspid valve replacement (TTVR) using the Evoque system safely and effectively treat severe tricuspid regurgitation in a patient with a failing heterotopic caval valve prosthesis?
Orthotopic transcatheter tricuspid valve replacement (TTVR) with the Evoque platform is a feasible and safe bailout strategy to correct severe tricuspid regurgitation in patients with a failing heterotopic caval valve system.
Answers are grounded in this paper and cite their sources.
Evoque TTVR may offer bailout feasibility after heterotopic caval valve failure; leaves open need for prospective safety and durability data.
BACKGROUND: Heterotopic caval valve implantation has emerged as a compassionate transcatheter option for patients with severe tricuspid regurgitation (TR) deemed unsuitable for edge-to-edge repair. However, long-term durability and management of device failure remain poorly defined. CASE SUMMARY: We report the case of a 70-year-old woman with prior heterotopic TricValve implantation because of massive TR, who presented with recurrent right-sided heart failure secondary to inferior vena cava prosthetic dysfunction. Multimodality imaging revealed the known significant TR and severe degeneration of the heterotopic valve at the inferior vena cava position, and confirmed anatomical suitability for orthotopic transcatheter tricuspid valve replacement (TTVR). The patient subsequently underwent successful Evoque TTVR, achieving complete TR abolition and TricValve unloading. DISCUSSION AND TAKE-HOME MESSAGES: This case highlights the versatility of TTVR as a comprehensive solution for clinically significant TR. Guided by advanced multimodality imaging, Evoque TTVR effectively provided definitive TR correction without any device interaction in a complex anatomical setting.
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Biroli et al. (2026) conducted a case report in Severe tricuspid regurgitation with recurrent right-sided heart failure secondary to inferior vena cava prosthetic dysfunction (n=1). Evoque transcatheter tricuspid valve replacement (TTVR) was evaluated on Complete tricuspid regurgitation abolition and symptom improvement. Evoque transcatheter tricuspid valve replacement successfully provided definitive tricuspid regurgitation correction without device interaction in a patient with a failing heterotopic caval valve.
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