Why the study?
Does a decrease in inappropriate left ventricular mass during antihypertensive treatment correlate with an increase in ejection fraction in patients with mild-to-moderate hypertension?
Population
168 patients with mild-to-moderate hypertension
Design
Cohort
Follow-up
4 months
Authors
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Supports targeting inappropriate LV mass to improve EF; hypothesis-generating and does not warrant practice change.
Does a decrease in inappropriate left ventricular mass during antihypertensive treatment correlate with an increase in ejection fraction in patients with mild-to-moderate hypertension?
Decreases in inappropriate left ventricular mass during antihypertensive therapy are strongly associated with increases in ejection fraction, suggesting excessive LV hypertrophy is a pathophysiological process reducing EF.
Woodiwiss et al. (2012) studied this question.
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