Ventricular Remodeling Does Not Accompany the Development of Heart Failure in Diabetic Patients After Myocardial Infarction
Why the study?
Is diabetes associated with increased left ventricular enlargement after myocardial infarction?
Population
512 patients after myocardial infarction from the Survival and Ventricular Enlargement echocardiographic…
Comparison
Diabetic status vs Nondiabetic status
Design
Cohort
Follow-up
2 years
Authors
Discussion
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Member takes
Implication
Diabetes was associated with less post-MI LV enlargement despite higher HF; leaves open non-remodeling mechanisms of excess risk.
Structured PICO
Is diabetes associated with increased left ventricular enlargement after myocardial infarction?
P
Population
512 patients (100 diabetic, 412 nondiabetic) after myocardial infarction from the Survival and Ventricular Enlargement (SAVE) echocardiographic substudy
I
Intervention
Diabetic status
C
Comparator
Nondiabetic status
O
Outcome
Left ventricular enlargement between baseline and 2 years after myocardial infarctionsurrogate
The increased incidence of heart failure after myocardial infarction in diabetic patients is not explained by a greater propensity for left ventricular remodeling.
Cite This Study
Solomon et al. (2002) studied this question.