Why the study?
Studies assessing the risk of atherosclerosis using carotid intima-media thickness in patients with scleroderma have shown conflicting results.
Does scleroderma increase subclinical atherosclerosis as measured by carotid intima-media thickness compared to healthy controls?
Does scleroderma increase subclinical atherosclerosis as measured by carotid intima-media thickness compared to healthy controls?
Patients with scleroderma have significantly higher carotid intima-media thickness compared to matched healthy controls, suggesting an increased burden of subclinical atherosclerosis associated with inflammatory activity.
Scleroderma was associated with higher CIMT; leaves open whether CIMT screening improves CV risk stratification in these patients.
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Ali et al. (2022) studied this question.
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