November 1, 1999Diabetes Care
Visceral adiposity and incident coronary heart disease in Japanese-American men. The 10-year follow-up results of the Seattle Japanese-American Community Diabetes Study.
Key result
Visceral adiposity (P=0.0090), fasting glucose (P=0.0002), and systolic blood pressure (P=0.0007) were significant independent risk factors for incident CHD in Japanese-American men over 10 years.
Why the study?
What are the independent risk factors for incident coronary heart disease in Japanese-American men?
Population
175 Japanese-American men without coronary heart disease (CHD) at baseline
Design
Cohort
Follow-up
up to 10 years
Authors
Discussion
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Implication
May inform risk stratification in Japanese-American men; leaves open whether modifying these factors reduces CHD.
Key Points
- The research aims to identify risk factors for incident coronary heart disease (CHD) among Japanese-American men.
- 175 Japanese-American men without CHD were followed for up to 10 years.
- Baseline assessments included blood pressure, BMI, plasma insulin, and cholesterol levels.
- Logistic regression was utilized to estimate the odds ratios for potential risk factors.
- 50 incident cases of CHD were identified during the follow-up period.
- Intra-abdominal fat (P=0.0090) and fasting glucose (P=0.0002) were significant risk factors for CHD.
- Multiple regression showed that visceral fat, blood pressure, and plasma glucose are critical independent risk factors.
Study Design
Type
Cohort (n=175)
Multicenter
No
Structured PICO
What are the independent risk factors for incident coronary heart disease in Japanese-American men?
P
Population
175 Japanese-American men without coronary heart disease (CHD) at baseline
O
Outcome
Incident coronary heart disease (CHD) diagnosed by electrocardiogram and clinical eventshard clinical
Visceral adiposity, blood pressure, and plasma glucose are important independent risk factors for incident coronary heart disease in Japanese-American men.
Cite This Study
Fujimoto et al. (1999) conducted a cohort in Incident coronary heart disease (CHD) (n=175). Visceral adiposity, blood pressure, and plasma glucose (risk factors) was evaluated on Incident coronary heart disease (CHD). Visceral adiposity (P=0.0090), fasting glucose (P=0.0002), and systolic blood pressure (P=0.0007) were significant independent risk factors for incident CHD in Japanese-American men over 10 years.