Why the study?
With few effective treatments for rising metabolic diseases, the vagus nerve is increasingly targeted for neuromodulation, prompting a review of vagal functional anatomy and its implications for therapy.
Does vagal neuromodulation improve outcomes in patients with metabolic disease?
Design
Review
Authors
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May limit sustained benefits of vagal neuromodulation in metabolic disease; leaves open whether specificity-optimized approaches will improve outcomes.
Does vagal neuromodulation improve outcomes in patients with metabolic disease?
Current vagal neuromodulation therapies for metabolic disease lack specificity, suggesting that genetically guided techniques or optimized stimulation parameters are needed for better efficacy.
Berthoud et al. (2019) studied this question.
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