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July 18, 2009World Journal of Surgery

Vagal Nerve Function in Obesity: Therapeutic Implications

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Key result

Interrupting abdominal bi-directional vagal transmission reduces hunger and promotes weight loss in the majority of patients.

Why the study?

Do interventions interrupting abdominal bi-directional vagal transmission reduce hunger and promote weight loss in patients with obesity?

Population

Patients with obesity and chronic overnutrition

Design

Review

Authors

JKJohn G. KralWPWencesley PaezBWBruce M. Wolfe

Discussion

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Overview

Hypothesis-generating for vagal interruption in obesity; prospective RCTs needed before clinical adoption.

Structured PICO

Do interventions interrupting abdominal bi-directional vagal transmission reduce hunger and promote weight loss in patients with obesity?

P
Population
Patients with obesity and chronic overnutrition
I
Intervention
Interventions interrupting abdominal bi-directional vagal transmission (including bariatric surgery)
O
Outcome
Weight loss and reduced hunger

Interrupting vagal transmission may be an effective therapeutic strategy for reducing hunger and promoting weight loss in obesity.

Cite This Study

Kral et al. (2009) conducted a review in Obesity. Interruption of abdominal bi-directional vagal transmission was evaluated on Hunger and weight loss. Interrupting abdominal bi-directional vagal transmission reduces hunger and promotes weight loss in the majority of patients.

synapsesocial.com/papers/6a11ceed1d1aaf85555633a6https://doi.org/10.1007/s00268-009-0138-8
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