Why the study?
A comprehensive assessment of the disease burden attributable to high systolic blood pressure in young adults was lacking.
What is the global disease burden and mortality attributable to high systolic blood pressure in young adults?
Population
Young adults globally from the Global Burden of Disease Study 2021
Comparison
High systolic blood pressure exposure stratified by sex, SDI level, region, nation, and specific disease
Design
Global Burden of Disease cross-sectional and trend analysis
Follow-up
1990 to 2021
Authors
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Substantial SBP-attributable burden in young adults via IHD supports early screening; cross-sectional data leave causal effects and intervention impact open.
What is the global disease burden and mortality attributable to high systolic blood pressure in young adults?
High systolic blood pressure causes a substantial and persistent global disease burden in young adults, particularly driven by ischemic heart disease, highlighting the need for early targeted interventions.
Dong et al. (2025) studied this question.