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May 22, 2026Open Access

Prevalence of anterior corneal scars impairing visual acuity after Descemet membrane endothelial keratoplasty (DMEK) and treatment by phototherapeutic keratectomy (PTK).

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Authors

JMJohannes Menzel-SeveringLSLorena StollenwerkKUKlara Ullrich

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Overview

Randomized trial investigates anterior corneal scars affecting vision post-DMEK, suggesting PTK can restore vision.

Key Points

  • The study aims to determine the prevalence of anterior corneal scars after DMEK and evaluate treatment outcomes with PTK.
  • Retrospective review of DMEK records from March 2014 to December 2020.
  • Patients categorized by postoperative best-corrected visual acuity (CDVA) into two groups based on their vision levels.
  • Follow-up assessment of group 1 patients treated with wavefront-guided PTK for scar treatment.
  • 11.2% of 420 eyes showed corneal scarring, with a mean CDVA of 0.66 ± 0.17.
  • Group 1 had 25% prevalence of scars compared to 6% in group 2 (p < 0.01).
  • Six months post-PTK, all treated cases showed no corneal scar and a CDVA of 1.0.

Cite This Study

Menzel-Severing et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff38cd674f7c03778c4afhttps://doi.org/10.48620/97833
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Visual and Structural Outcomes of Descemet Membrane Endothelial Keratoplasty for Failed Penetrating Keratoplasty: A Systematic Review and Meta-Analysis2026
  2. 2Anterior segment optical coherence tomography enables repeat Descemet Membrane Endothelial Keratoplasty instead of penetrating keratoplasty in a patient with a prominent corneal opacity following DMEK failure: a case report2026
  3. 3Phototherapeutic Keratectomy Results for the Treatment of Corneal Scarring After Pterygium Excision2024
  4. 4Recurrence Rate After Phototherapeutic Keratectomy in Epithelial–Stromal TGFBI Corneal Dystrophies Compared With Epithelial Basement Membrane Dystrophy2026
  5. 5Descemet membrane endothelial keratoplasty and penetrating keratoplasty in pseudophakic bullous keratopathy: comparison of visual outcomes, graft survival rates, and complications2024