Key result
PCI successfully treats NSTEMI in a dextrocardia patient using adapted catheter selection and fluoroscopy.
Why the study?
Dextrocardia with situs inversus totalis is a rare congenital anomaly that complicates the diagnosis and percutaneous coronary intervention for acute coronary syndromes due to mirror-image anatomy.
Case Report (n=1)
This case highlights the necessity of ECG lead reversal and adapted PCI techniques for managing acute coronary syndrome in patients with dextrocardia and situs inversus.
Alerts clinicians to atypical ECGs in dextrocardia for timely NSTEMI diagnosis; hypothesis-generating for management in congenital anomalies.
BACKGROUND: Dextrocardia with situs inversus totalis is a rare congenital anomaly that complicates diagnosis and percutaneous coronary intervention (PCI) for acute coronary syndromes due to mirror-image anatomy. CASE SUMMARY: A 50-year-old man with situs inversus totalis presented with severe angina, syncope, and markedly elevated troponin (non-ST-segment elevation myocardial infarction). Initial electrocardiogram (ECG) showed right axis deviation and atypical R-wave progression. Lead reversal confirmed ischemic changes. Coronary angiography revealed complete right coronary artery occlusion and multivessel disease. The right coronary artery was successfully revascularized, achieving TIMI flow grade 3. DISCUSSION: This case illustrates the rare combination of acute coronary syndrome in a patient with situs inversus. It reinforces that standard myocardial infarction management protocols must be applied with necessary, specific anatomical adaptations in both ECG interpretation and PCI technique. TAKE-HOME MESSAGE: Accurate ECG interpretation in dextrocardia requires lead reversal, and successful PCI in situs inversus depends on adaptation of catheter selection and fluoroscopic imaging.
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Sánchez et al. (2026) conducted a case report in Non-ST-segment elevation myocardial infarction (n=1). Percutaneous coronary intervention was evaluated. Percutaneous coronary intervention was successfully performed in a patient with dextrocardia and NSTEMI by adapting catheter selection and fluoroscopic imaging.
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