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July 19, 2005Annals of Internal Medicine

Cost-Effectiveness of Full Medicare Coverage of Angiotensin-Converting Enzyme Inhibitors for Beneficiaries with Diabetes

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Why the study?

Does Medicare first-dollar coverage of ACE inhibitors improve cost-effectiveness and health outcomes in 65-year-old Medicare beneficiaries with diabetes?

Population

65-year-old Medicare beneficiary with diabetes

Comparison

Medicare first-dollar coverage of ACE inhibitors vs Current practice and the new Medicare drug benefit

Design

Other

Follow-up

Lifetime

Authors

ARAllison B. RosenAmerican Cancer SocietyMHMary Beth HamelBeth Israel Deaconess Medical Center
Milton C. Weinstein
Milton C. WeinsteinUniversity of California, Riverside

Discussion

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Member takes

Overview

May support first-dollar ACE inhibitor coverage in diabetic Medicare patients; leaves open prospective confirmation before policy change.

Structured PICO

Does Medicare first-dollar coverage of ACE inhibitors improve cost-effectiveness and health outcomes in 65-year-old Medicare beneficiaries with diabetes?

P
Population
65-year-old Medicare beneficiary with diabetes
I
Intervention
Medicare first-dollar coverage (no cost sharing) of ACE inhibitors
C
Comparator
Current practice (no coverage) and the new Medicare drug benefit
O
Outcome
Costs (2003 U.S. dollars), quality-adjusted life-years (QALYs), life-years, and incremental cost-effectiveness

First-dollar Medicare coverage of ACE inhibitors for diabetic beneficiaries is a dominant strategy that extends life and reduces overall Medicare program costs.

Limitations

  • Results depend on accuracy of the underlying data and assumptions
  • The effect of more generous drug coverage on medication adherence is uncertain

Cite This Study

Rosen et al. (2005) studied this question.

synapsesocial.com/papers/6a0ffd162badbc352aff186chttps://doi.org/10.7326/0003-4819-143-2-200507190-00007
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Use of Enalapril To Attenuate Decline in Renal Function in Normotensive, Normoalbuminuric Patients with Type 2 Diabetes Mellitus1998 · 388 citations
  2. 2Randomized placebo-controlled trial of perindopril in normotensive, normoalbuminuric patients with type 1 diabetes mellitus2001 · 59 citations
  3. 3Is ACE Inhibition with Lisinopril Helpful in Diabetic Neuropathy?1995 · 92 citations
  4. 4The Continuing Epidemics of Obesity and Diabetes in the United States2001 · 2,749 citations
  5. 5Implementation of a Voluntary Hospitalist Service at a Community Teaching Hospital: Improved Clinical Efficiency and Patient Outcomes2002 · 222 citations