Key result
Negative intrathoracic pressure during the Müller maneuver decreased the velocity of fiber shortening and ejection fraction by increasing left ventricular transmural pressures and afterload.
Why the study?
Do Valsalva and Müller maneuvers affect left ventricular performance in patients?
Population
8 patients with implanted intramyocardial markers
Design
Other
Authors
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May impair LV performance in acute pulmonary disease; leaves open clinical relevance of maneuvers.
Observational (n=8)
Do Valsalva and Müller maneuvers affect left ventricular performance in patients?
Large intrathoracic-pressure changes, such as those in acute pulmonary disease, can negatively influence cardiac performance by increasing left ventricular transmural pressures and afterload.
Buda et al. (1979) conducted an observational in Left ventricular dysfunction related to respiratory disease (n=8). Valsalva and Müller maneuvers was evaluated on Velocity of fiber shortening (VCF) and left ventricular volume. Negative intrathoracic pressure during the Müller maneuver decreased the velocity of fiber shortening and ejection fraction by increasing left ventricular transmural pressures and afterload.
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