Key result
Valsalva maneuver associated with decreased LV early inflow velocity and E/A ratio, suggesting impeded diastole.
Why the study?
Does positive intrathoracic pressure induced by a Valsalva maneuver alter left ventricular filling parameters in healthy subjects?
Population
30 healthy subjects
Comparison
Valsalva maneuver with a load of 40 mmHg lasting… vs At rest (baseline values prior to maneuver)
Design
Other
Follow-up
10 seconds
Authors
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Alerts clinicians to potential confounding of diastolic parameters by respiratory maneuvers; leaves open effects in cardiovascular disease.
Observational (n=30)
Does positive intrathoracic pressure induced by a Valsalva maneuver alter left ventricular filling parameters in healthy subjects?
Positive intrathoracic pressure during the Valsalva maneuver significantly alters LV filling parameters, likely by impeding LV diastolic motion and increasing flow resistance.
Zhang et al. (2015) conducted an observational in Healthy (n=30). Valsalva maneuver (positive intrathoracic pressure) vs. At rest was evaluated on Left ventricular filling parameters (E, A, E/A ratio, e', E/e' ratio). A Valsalva maneuver significantly decreased left ventricular early inflow velocity and the E/A ratio in healthy subjects, suggesting positive intrathoracic pressure impedes diastolic motion.
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