Why the study?
Does the clinical profile and prognosis differ among patients with HFrEF, HFmrEF, and HFpEF according to the 2016 ESC guidelines?
Does the clinical profile and prognosis differ among patients with HFrEF, HFmrEF, and HFpEF according to the 2016 ESC guidelines?
Patients with HFmrEF share similar cardiovascular risk factors, medical history, and prognosis as those with HFrEF and HFpEF, questioning the clinical relevance of the HFmrEF classification.
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Comparable survival across HF phenotypes in this cohort cautions against routine HFmrEF distinctions in practice; leaves open classification utility pending prospective validation.
Delepaul et al. (2017) studied this question.
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