Does a carbohydrate-reduced, fat-modified diet improve haemostatic variables in men with hyperlipidaemia?
Dietary treatment of hyperlipidaemia improves haemostatic function, suggesting a potential mechanism for reducing ischaemic heart disease risk.
The haemostatic function of 11 men with hyperlipidaemia was measured before and after they were treated with a carbohydrate-reduced, fat-modified diet. After treatment, which significantly reduced serum triglyceride and cholesterol concentrations, they showed a significant fall in mean levels of clotting factors VII, VIII, and X and a rise in fibrinolytic activity. These findings suggest that haemostatic function may be important in the pathogenesis of ischaemic heart disease.
Elkeles et al. (Sat,) studied this question.