Why the study?
Does a carbohydrate-reduced, fat-modified diet improve haemostatic variables in men with hyperlipidaemia?
Does a carbohydrate-reduced, fat-modified diet improve haemostatic variables in men with hyperlipidaemia?
Dietary treatment of hyperlipidaemia improves haemostatic function, suggesting a potential mechanism for reducing ischaemic heart disease risk.
Dietary changes were associated with improved haemostatic function in hyperlipidaemic men; hypothesis-generating for IHD risk reduction, pending randomized trials.
The haemostatic function of 11 men with hyperlipidaemia was measured before and after they were treated with a carbohydrate-reduced, fat-modified diet. After treatment, which significantly reduced serum triglyceride and cholesterol concentrations, they showed a significant fall in mean levels of clotting factors VII, VIII, and X and a rise in fibrinolytic activity. These findings suggest that haemostatic function may be important in the pathogenesis of ischaemic heart disease.
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Elkeles et al. (1980) studied this question.
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