Why the study?
Does static handgrip exercise and postexercise ischemia elicit a different arterial blood pressure response in patients with HFpEF compared to older, healthy controls?
Does static handgrip exercise and postexercise ischemia elicit a different arterial blood pressure response in patients with HFpEF compared to older, healthy controls?
Patients with HFpEF exhibit a reduced pressor response to exercise, potentially mediated by a blunted muscle metaboreflex, indicating impaired neural cardiovascular control.
The current investigation has identified a diminution in the exercise-induced rise in arterial blood pressure (BP) that persisted during postexercise ischemia (PEI) in an intensity-dependent manner in patients with heart failure with preserved ejection fraction (HFpEF) compared with older, healthy controls. These findings suggest that the pressor response to exercise is reduced in patients with HFpEF, and this deficit may be mediated, in part, by a blunted muscle metaboreflex, highlighting the consequences of impaired neural cardiovascular control during exercise in this patient group.
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Bunsawat et al. (2023) studied this question.
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