C-Reactive Protein Is Related to Arterial Wave Reflection and Stiffness in Asymptomatic Subjects From the Community
Population
214 asymptomatic individuals from the community, mean age 59 years, 53% men.
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
Does not support practice change; leaves open whether CRP is a modifiable target for arterial health.
Structured PICO
P
Population
214 asymptomatic individuals from the community, mean age 59 years, 53% men.
O
Outcome
Relationship of C-reactive protein (CRP) to measures of arterial wave reflection and stiffness (aortic augmentation index [AIX], carotid-femoral pulse wave velocity [PWV], and pulse pressure)surrogate
Elevated CRP levels are independently associated with increased arterial stiffness and wave reflection in asymptomatic individuals, suggesting a link between systemic inflammation and vascular dysfunction.
Cite This Study
Kullo et al. (2005) studied this question.