What question did this study set out to answer?

To evaluate the prognostic impact of left ventricular mass that exceeds the individual hemodynamic load required to maintain circulation in hypertensive patients.

October 1, 2002HypertensionOpen Access

Prognosis of Inappropriate Left Ventricular Mass in Hypertension

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Why the study?

Does inappropriate left ventricular mass predict cardiovascular events in hypertensive patients?

Key Points

To evaluate the prognostic impact of left ventricular mass that exceeds the individual hemodynamic load required to maintain circulation in hypertensive patients.
Prospective multicenter study (MAVI study, Italy) assessing 1,019 hypertensive adults (627 women, 392 men) free of baseline cardiovascular disease and type 1 diabetes.
Calculated inappropriate left ventricular (LV) mass as a percentage of predicted ideal mass based on sex, height (m^2.7), and stroke work, with a follow-up of 35 ± 11 months.
A total of 52 fatal or nonfatal primary cardiovascular events occurred during follow-up.
LV mass as a percentage of predicted value significantly predicted cardiovascular events (P < 0.01), independent of age, systolic blood pressure, sex, glycemia, BMI, and antihypertensive treatments.
Cardiovascular risk increased stepwise across quintiles of predicted LV mass (P < 0.01), providing incremental prognostic value over standard LV mass measurement (P < 0.01).

Structured PICO

Does inappropriate left ventricular mass predict cardiovascular events in hypertensive patients?

Population

1019 white hypertensives (627 women [24% obese] and 392 men [17% obese]) without prevalent cardiovascular disease or type 1 diabetes, from the Italian multicenter, prospective study MAVI.

Intervention

Inappropriate left ventricular (LV) mass (excess of echocardiographic LV mass in relation to individual ideal value predicted by gender, stroke work, and height)

Comparator

Appropriate LV mass or lower quintiles of LV mass

Outcome

Fatal or nonfatal primary cardiovascular eventshard clinical

Inappropriate left ventricular mass provides incremental prognostic value for cardiovascular events beyond traditional LV mass assessment in hypertensive patients.

Discussion

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Implication

May refine CV risk stratification in hypertension; leaves open whether inappropriate LV mass adds value beyond standard measures.

Cite This Study

Simone et al. (2002) studied this question.

synapsesocial.com/papers/6a1033e2d13714ec96ff5b85 https://doi.org/10.1161/01.hyp.0000034740.99323.8a

Topics

Hypertension management Echocardiography Women and heart disease

View Full Paper

Ask AI

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Prognosis of Inappropriate Left Ventricular Mass in Hypertension

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Prognosis of Inappropriate Left Ventricular Mass in Hypertension

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider