August 1, 1988Circulation
Experimental validation of Doppler echocardiographic measurement of volume flow through the stenotic aortic valve.
Key result
Electromagnetic flow measurement was highly correlated with direct volume flow collection (r=0.97) in a canine model of aortic stenosis, serving as a reference for Doppler echocardiography validation.
Why the study?
Does Doppler echocardiography accurately measure volume flow through a stenotic aortic valve compared to electromagnetic flow measurement in an experimental canine model?
Population
12 adult mongrel dogs in an open-chest model with native leaflets sutured together to create variable…
Comparison
Doppler echocardiography measurement of… vs Electromagnetic flowmeter measurement of…
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Validates electromagnetic flowmetry as reference in canine aortic stenosis models; leaves open clinical translation for Doppler echocardiography.
Structured PICO
Does Doppler echocardiography accurately measure volume flow through a stenotic aortic valve compared to electromagnetic flow measurement in an experimental canine model?
P
Population
12 adult mongrel dogs (mean weight 25 kg) in an open-chest model with native leaflets sutured together to create variable degrees of acute aortic stenosis
I
Intervention
Doppler echocardiography measurement of transaortic cardiac output in the left ventricular outflow tract
C
Comparator
Electromagnetic flowmeter measurement of transaortic flow (and timed collection of total aortic flow)
O
Outcome
Accuracy of Doppler volume-flow measurement compared to electromagnetic flowmetersurrogate
Main Result
Effect estimate: r = 0.97
Cite This Study
Otto et al. (1988) studied Aortic stenosis (n=12). Doppler echocardiography vs. Electromagnetic flowmeter was evaluated on Accuracy of volume flow measurement (r = 0.97). Electromagnetic flow measurement was highly correlated with direct volume flow collection (r=0.97) in a canine model of aortic stenosis, serving as a reference for Doppler echocardiography validation.