March 31, 2022Journal of TechniquesOpen Access

Comparison between Sevoflurane and Isoflurane Effects on Hemodynamic Status

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Why the study?

Volatile anaesthetics cause hypotension via central, autonomic, myocardial, and vascular smooth muscle effects, prompting a comparison of sevoflurane and isoflurane effects on pulse rate and mean blood pressure during general anaesthesia.

Does sevoflurane compared to isoflurane improve hemodynamic stability (pulse rate and mean blood pressure) in patients undergoing general anesthesia?

Population

30 patients aged 7-68 years undergoing surgery under general anaesthesia

Comparison

Sevoflurane vs isoflurane

Design

Two-centre prospective study

Authors

AHAdel Amen HamaMiddle Technical University

Discussion

Member takes

Implication

Supports similar hemodynamic profiles with either agent; leaves open need for RCTs to confirm equivalence.

Structured PICO

Does sevoflurane compared to isoflurane improve hemodynamic stability (pulse rate and mean blood pressure) in patients undergoing general anesthesia?

Population

30 patients between 7-68 years old (13 male, 17 female) undergoing surgery requiring general anesthesia, fasting for 8-10 hours before the proposed time of surgery.

Intervention

Sevoflurane (1.8%) inhalational agent added to standard premedication (tramadol 1.5 mg/kg, dexamethasone 0.1 mg/kg, metoclopramide 0.1 mg/kg, ranitidine 0.9 mg/kg) and intravenous induction (propofol, ketamine 0.5-1.5 mg/kg, atracurium 0.5 mg/kg).

Comparator

Isoflurane (1.2%) inhalational agent added to the same standard premedication and intravenous induction.

Outcome

Pulse rate and mean blood pressure recorded at baseline, intubation, 5, 10, 15, 20, 25, 30, and 40 minutes of operation, extubation, and recovery.surrogate

Sevoflurane and isoflurane demonstrate comparable hemodynamic stability regarding pulse rate and mean blood pressure during general anesthesia.

Cite This Study

Adel Amen Hama (2022) studied this question.

synapsesocial.com/papers/6a1060a25725bbd5cc60ecb5 https://doi.org/10.51173/jt.v4i1.416

View Full Paper

Ask AI

Bookmark

Comparison between Sevoflurane and Isoflurane Effects on Hemodynamic Status

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Comparison between Sevoflurane and Isoflurane Effects on Hemodynamic Status

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider