Why the study?
The influence of MSNA responses on local vascular conductance during exercise was not well established, particularly given that variations in exercise mode and active muscle mass can produce divergent MSNA responses.
Does small- versus large-muscle mass dynamic exercise alter muscle sympathetic nerve activity and vascular conductance in the inactive leg?
Population
35 participants
Comparison
Rhythmic handgrip vs one-leg cycling vs concurrent exercise vs rest
Design
Randomized crossover physiological study
Authors
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MSNA burst amplitude may modulate inactive-limb conductance during low-intensity exercise; hypothesis-generating for sympathetic control of vascular tone.
Does small- versus large-muscle mass dynamic exercise alter muscle sympathetic nerve activity and vascular conductance in the inactive leg?
Changes in MSNA burst amplitude, rather than frequency, are inversely associated with SFA vascular conductance during low-intensity dynamic exercise.
Doherty et al. (2019) studied this question.
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