Lifetime History of Major Depression Predicts the Development of the Metabolic Syndrome in Middle-Aged Women
Why the study?
Does a lifetime history of major depression predict the development of the metabolic syndrome in middle-aged women?
Population
429 women in the menopausal transition from one site of the Study of Women's Health Across the Nation
Comparison
Lifetime major depression history or current… vs No lifetime major depression history or current…
Design
Cohort
Follow-up
seven annual follow-up evaluations
Authors
Discussion
Loading...
Member takes
Implication
Depression history may flag higher metabolic risk in middle-aged women; leaves open whether treatment alters incidence.
Structured PICO
Does a lifetime history of major depression predict the development of the metabolic syndrome in middle-aged women?
P
Population
429 women (34.5% African-American) in the menopausal transition from one site of the Study of Women's Health Across the Nation (SWAN)
I
Intervention
Lifetime major depression history or current major depressive episode at baseline
C
Comparator
No lifetime major depression history or current major depressive episode at baseline
O
Outcome
Incidence of the metabolic syndrome based on National Cholesterol Education Program (NCEP) criteriasurrogate
A lifetime history of major depression or a current major depressive episode is a significant predictor of the onset of metabolic syndrome in middle-aged women.
Cite This Study
Goldbacher et al. (2009) studied this question.