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August 8, 2024Ultrasound in Medicine & BiologyOpen Access

EasyPISA: Automatic Integrated PISA Measurements of Mitral Regurgitation From 2-D Color-Doppler Using Deep Learning

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Why the study?

The PISA method for MR quantification exhibits high inter-observer variability and inaccuracies in cases of non-hemispherical flow convergence and non-holosystolic MR.

Does the EasyPISA deep learning framework provide accurate automated integrated PISA measurements of mitral regurgitation compared to manual PISA and cMRI?

Population

54 patients for model training and 26 MR patient examinations for retrospective testing

Comparison

EasyPISA automated measurements vs reference PISA and cMRI measurements

Design

Retrospective deep learning model development and validation study

Authors

SWSigurd Vangen WifstadNorwegian University of Science and TechnologyHKHenrik Agerup KildahlNorwegian University of Science and TechnologyEHEspen HolteCardiac Imaging

Discussion

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Implication

May reduce interobserver variability in mitral regurgitation assessment; leaves open prospective validation before routine adoption.

Structured PICO

Does the EasyPISA deep learning framework provide accurate automated integrated PISA measurements of mitral regurgitation compared to manual PISA and cMRI?

P
Population
54 patients (1171 images from 196 recordings) for training, and 26 mitral regurgitation patient examinations for retrospective testing (13 with cMRI)
I
Intervention
EasyPISA (deep learning framework using UNet/Attention UNet for automated integrated PISA measurements from 2-D color-Doppler sequences)
C
Comparator
Reference manual PISA regurgitant volume (RVol) measurements, severity grades, and cMRI RVol measurements
O
Outcome
Accuracy and correlation metrics including precision, recall, dice score, flow rate error, intraclass correlation coefficient (ICC) with reference PISA and cMRI, and AUC for severity gradessurrogate

EasyPISA provides a fully automated deep learning approach for quantifying mitral regurgitation from 2-D color-Doppler, showing good correlation with manual PISA and cMRI, which may reduce workload and inter-observer variability.

Cite This Study

Wifstad et al. (2024) studied this question.

synapsesocial.com/papers/6a109db4b6f5ee040160de62https://doi.org/10.1016/j.ultrasmedbio.2024.06.008

Topics

Mitral valve intervention
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