Quantification of Chronic Functional Mitral Regurgitation by Automated 3-Dimensional Peak and Integrated Proximal Isovelocity Surface Area and Stroke Volume Techniques Using Real-Time 3-Dimensional Volume Color Doppler Echocardiography
Why the study?
Does automated 3D PISA and stroke volume technique accurately quantify mitral regurgitation compared to cardiac magnetic resonance imaging in patients with functional MR?
Population
In vitro model of mitral regurgitation and 30 patients with functional mitral regurgitation
Comparison
Automated 3-dimensional proximal isovelocity… vs 2-dimensional PISA, flowmeter, and cardiac…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Supports integrated 3D PISA for functional MR quantification; hypothesis-generating and requires prospective outcome validation before practice change.
Structured PICO
Does automated 3D PISA and stroke volume technique accurately quantify mitral regurgitation compared to cardiac magnetic resonance imaging in patients with functional MR?
P
Population
In vitro model of mitral regurgitation and 30 patients with functional mitral regurgitation
I
Intervention
Automated 3-dimensional (3D) proximal isovelocity surface area (PISA) and stroke volume technique using real-time volume color flow Doppler transthoracic echocardiography
C
Comparator
2-dimensional (2D) PISA, flowmeter (in vitro), and cardiac magnetic resonance imaging (in patients)
O
Outcome
Accuracy of effective regurgitant orifice area and regurgitant volume measurementssurrogate
Automated real-time 3D volume color flow Doppler-based integrated PISA provides a more accurate quantification of functional mitral regurgitation than 2D PISA, with results comparable to cardiac magnetic resonance imaging.
Cite This Study
Thavendiranathan et al. (2012) studied this question.