Why the study?
Is obstructive sleep apnea independently associated with insulin resistance in subjects without known diabetes mellitus?
Population
270 consecutive subjects who were referred for polysomnography and who did not have known diabetes mellitus
Comparison
Obstructive sleep apnea defined as an… vs Subjects without OSA (AHI <5)
Design
Cross-sectional
Authors
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OSA parameters associated with insulin resistance independent of obesity; hypothesis-generating and requires prospective confirmation before clinical implications.
Is obstructive sleep apnea independently associated with insulin resistance in subjects without known diabetes mellitus?
Obstructive sleep apnea is independently associated with insulin resistance, even after adjusting for obesity, suggesting a potential mechanism for its atherogenic risk.
Ip et al. (2002) studied this question.
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