Why the study?
Is obstructive sleep apnea associated with increased insulin resistance and metabolic risk factors in men without cardiovascular disease?
Population
42 men attending a sleep clinic, free of diabetes, clinically demonstrable cardiovascular disease, marked…
Comparison
Obstructive sleep apnea vs No obstructive sleep apnea, matched for age +/…
Design
Case-control
Authors
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OSA was associated with higher insulin resistance and LDL in men without CVD; leaves open causal role in vascular risk, needing prospective confirmation.
Is obstructive sleep apnea associated with increased insulin resistance and metabolic risk factors in men without cardiovascular disease?
Obstructive sleep apnea is independently associated with increased insulin resistance and atherogenic lipid profiles in men without baseline cardiovascular disease, suggesting a mechanism for increased vascular risk.
McArdle et al. (2006) studied this question.
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