Key result
A 2D left ventricle hypertrophy score improved diagnostic sensitivity for hypertrophic cardiomyopathy compared to maximal wall thickness, particularly in adults <50 years (67% vs 53%, P<0.03).
Why the study?
Does a 2D LVH score improve diagnostic sensitivity for familial hypertrophic cardiomyopathy compared to conventional maximal wall thickness in adults from genotyped families?
Population
237 adults from genotyped families with hypertrophic cardiomyopathy, split into a derivation sample and a…
Comparison
2D left ventricle hypertrophy score determined… vs Conventional maximal wall thickness measurement
Design
Cross-sectional
Authors
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May support 2D LVH scoring to enhance HCM detection in adults <50; leaves open prospective validation in genotyped families.
Observational (n=237)
Does a 2D LVH score improve diagnostic sensitivity for familial hypertrophic cardiomyopathy compared to conventional maximal wall thickness in adults from genotyped families?
Absolute Event Rate: 73% vs 62.5%
A new 2D LVH score improves diagnostic sensitivity for familial hypertrophic cardiomyopathy compared to conventional maximal wall thickness, particularly in adults under 50 years of age.
Forissier et al. (2005) conducted an observational in Familial hypertrophic cardiomyopathy (n=237). 2D left ventricle hypertrophy (2D LVH) score vs. Maximal wall thickness (MWT) measurement was evaluated on Diagnostic sensitivity for hypertrophic cardiomyopathy. A 2D left ventricle hypertrophy score improved diagnostic sensitivity for hypertrophic cardiomyopathy compared to maximal wall thickness, particularly in adults <50 years (67% vs 53%, P<0.03).
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