Key result
Higher culprit-territory regional myocardial work index is linked to ~40% lower odds of early LV remodeling.
Why the study?
Adverse LV remodelling post-STEMI portends poor outcomes, and whether non-invasive global and regional LV myocardial work before discharge predicts this remodelling remained to be evaluated.
Does regional myocardial work index in the culprit vessel territory predict early LV remodelling in STEMI patients after primary PCI?
Comparison
Global and regional LV myocardial work indices vs adverse LV remodelling status
Design
Cohort study
Follow-up
3 months
Authors
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May support post-STEMI risk stratification; leaves open incremental value beyond troponin and LVEDV.
Cohort (n=350)
Does regional myocardial work index in the culprit vessel territory predict early LV remodelling in STEMI patients after primary PCI?
Effect estimate: OR 0.602 (95% CI 0.383-0.945)
p-value: p=0.027
Regional myocardial work index in the culprit vessel territory assessed before discharge independently predicts early adverse LV remodelling in STEMI patients treated with primary PCI.
Lustosa et al. (2020) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=350). Regional myocardial work index (MWI) in the culprit vessel territory was evaluated on Early LV remodelling defined as increase in LV end-diastolic volume (LVEDV) ≥20% at 3 months after STEMI (OR 0.602, 95% CI 0.383-0.945, p=0.027). Regional myocardial work index in the culprit vessel territory before discharge was independently associated with early adverse LV remodelling at 3 months (OR 0.602; 95% CI 0.383-0.945; P=0.027).
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