Why the study?
Does low molecular weight heparin plus aspirin improve live birth rates in women with recurrent pregnancy loss and autoantibodies or coagulation abnormalities compared to aspirin alone?
Population
88 women with a history of recurrent pregnancy loss and at least 1 of the following: antiphospholipid…
Comparison
Low molecular weight heparin plus aspirin vs Aspirin (ASA) alone
Design
RCT, Stratified by aPL status and history of early versus late pregnancy losses
Authors
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Adding LMWH to ASA does not improve live births; challenges routine combination use and supports ASA monotherapy in this population.
Does low molecular weight heparin plus aspirin improve live birth rates in women with recurrent pregnancy loss and autoantibodies or coagulation abnormalities compared to aspirin alone?
Low molecular weight heparin plus aspirin did not improve live birth rates compared to aspirin alone in women with recurrent pregnancy loss and autoantibodies or coagulation abnormalities.
Laskin et al. (2009) studied this question.
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