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June 1, 2004European Heart JournalOpen Access

Haemostatic/inflammatory markers predict 10-year risk of IHD at least as well as lipids: the Caerphilly collaborative studies

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Why the study?

Do haemostatic/inflammatory markers predict 10-year risk of IHD as well as plasma lipids in men?

Population

4860 men from two UK populations screened for evidence of IHD between 1979 and 1983

Comparison

Haemostatic/inflammatory risk markers vs Plasma lipids

Design

Cohort

Follow-up

10 years

Authors

JYJ. W. G. YarnellQueen's University Belfast

Discussion

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Implication

Haemostatic/inflammatory markers merit evaluation in IHD risk models for men; leaves open their added value beyond lipids in prospective validation.

Structured PICO

Do haemostatic/inflammatory markers predict 10-year risk of IHD as well as plasma lipids in men?

P
Population
4860 men from two UK populations screened for evidence of IHD between 1979 and 1983
I
Intervention
Haemostatic/inflammatory risk markers (fibrinogen, viscosity, and white cell count)
C
Comparator
Plasma lipids (total cholesterol, HDL-cholesterol, triglycerides)
O
Outcome
Incident ischaemic heart disease (fatal, non-fatal or silent myocardial infarction) at 10 yearshard clinical

Haemostatic and inflammatory markers predict the 10-year risk of ischaemic heart disease at least as well as traditional lipid markers in men.

Cite This Study

J. W. G. Yarnell (2004) studied this question.

synapsesocial.com/papers/6a10e7be2c0ee39daeee4dffhttps://doi.org/10.1016/j.ehj.2004.04.011
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