Key result
Depression linked to higher SBP and carotid arterial stiffness versus healthy controls.
Why the study?
Depression is correlated with cardiovascular diseases, but the mechanisms affecting morbidity and mortality are not fully identified. The authors sought to evaluate ultrasonography-diagnosed arterial stiffness in depression patients compared with healthy controls.
Is depression associated with increased arterial stiffness compared to healthy controls?
Case-Control (n=70)
Is depression associated with increased arterial stiffness compared to healthy controls?
Depression is associated with increased systolic blood pressure and carotid elastic modulus, suggesting increased arterial stiffness and cardiovascular risk.
May indicate elevated CV risk in depression; hypothesis-generating and requires prospective confirmation before practice implications.
Background: It has been known that there is a significant correlation between depression and cardiovascular diseases. However, the reasons behind this correlation that could affect mortality and morbidity were not fully identified. The present study aimed to analyze arterial stiffness diagnosed with ultrasonography, which could be associated with cardiovascular disease risks in depression patients, and to compare the findings with those of healthy controls. Methods: The study was conducted with 35 depression patients and 35 healthy individuals. Routine complete blood and biochemistry tests were requested for all patients, and their weight and height, waist circumference, and diastolic and systolic arterial blood pressure were measured. Femoral and carotid artery intima-media thickness and other arterial stiffness parameters were determined with Doppler ultrasonography. Results: = -0.389). Conclusion: It was determined that the systolic blood pressure and carotid elastic modulus arterial stiffness parameters were significantly higher in depression patients. Measurable arterial stiffness parameters should be investigated in depression patients as cardiovascular risk markers. Furthermore, the determination of the effects of psychotropic drugs employed in arterial stiffness treatment could play an important role in the determination of cardiovascular disease risk in these patients.
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Emir et al. (2023) conducted a case-control in Depression (n=70). Depression vs. Healthy controls was evaluated on Arterial stiffness parameters and systolic blood pressure. Depression was associated with significantly higher systolic blood pressure and carotid elastic modulus arterial stiffness parameters compared to healthy controls.
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