Why the study?
Does quantitative analysis of 201Tl myocardial ECT improve diagnostic accuracy for infarct location and size compared to 2D imaging in patients with old myocardial infarction?
Does quantitative analysis of 201Tl myocardial ECT improve diagnostic accuracy for infarct location and size compared to 2D imaging in patients with old myocardial infarction?
Quantitative analysis of 201Tl myocardial ECT provides an objective and reliable non-invasive method for assessing infarct size and location in patients with old myocardial infarction.
左室造影(LVG)を施行した陳旧性心筋梗塞患者52名を対象として,安静時における二次元201Tl心筋像(二次元心筋像)および201Tl心筋emission computed tomography (ECT)像のcircumferential profile解析を行ない,梗塞の部位および大きさの診断におけるECT定量解析の有用性を検討した.健常者の長軸および短軸ECT像より求めた正常下限profile curveをもとに判定した梗塞領域は, LVGにおける壁運動異常領域とよく一致し,二次元心筋像の定量解析よりも有意に診断感度および精度が向上した.短軸ECT像から求めた全左室心筋容積に対する梗塞領域容積の百分率(%infarct size)は, %ACS (percent abnormally contracting segment: LVGの拡張期左室全周長に対する無または奇異性収縮領域周囲長の比)との間に, r=0.74(p<0.0001)の有意な正相関を,またLVGより求めた左室駆出率との間にr=-0.53(p<0.0001)の有意な負相関を示した. 201Tl心筋ECT像のcircumferential profile解析は,陳旧性心筋梗塞の部位および大きさの診断において,客観的かつ信頼性の高い非観血的方法と結論された.
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Matsushima et al. (1985) studied this question.
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