Key result
A chronic total occlusion in an infarct-related artery independently predicted higher VT recurrence after ablation compared to no occlusion (47% vs 16%; HR 4.05, P=0.004).
Why the study?
Does the presence of a chronic total occlusion in an infarct-related artery predict ventricular tachycardia recurrence in patients with prior myocardial infarction undergoing VT ablation?
Cohort (n=84)
No
Does the presence of a chronic total occlusion in an infarct-related artery predict ventricular tachycardia recurrence in patients with prior myocardial infarction undergoing VT ablation?
Effect estimate: HR 4.05
Absolute Event Rate: 47% vs 16%
p-value: p=0.004
The presence of a chronic total occlusion in an infarct-related artery is a strong independent predictor of ventricular tachycardia recurrence after ablation in patients with prior myocardial infarction.
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May inform post-ablation risk stratification in post-MI patients; hypothesis-generating for targeted CTO interventions.
Marco et al. (2015) conducted a cohort in Ventricular tachycardia with prior myocardial infarction (n=84). Chronic total occlusion in an infarct-related artery (IRA-CTO) vs. Absence of IRA-CTO was evaluated on Ventricular tachycardia (VT) recurrence (HR 4.05, p=0.004). A chronic total occlusion in an infarct-related artery independently predicted higher VT recurrence after ablation compared to no occlusion (47% vs 16%; HR 4.05, P=0.004).
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