Key result
Comprehensive fetal echocardiography achieves a 95% prenatal detection rate for significant cardiovascular malformations.
Why the study?
The study was conducted to report recent experience with prenatal detection of significant cardiovascular malformations in Nevada's state-wide maternal population receiving prenatal care.
What is the prenatal detection rate of significant cardiovascular malformations in a state-wide maternal population receiving routine prenatal care?
Observational (n=390)
Yes
What is the prenatal detection rate of significant cardiovascular malformations in a state-wide maternal population receiving routine prenatal care?
Prenatal detection of significant cardiovascular malformations in Nevada reached 95% in the most recent year, demonstrating highly effective state-wide screening.
Answers are grounded in this paper and cite their sources.
Supports high prenatal detection with comprehensive screening in routine care; leaves open generalizability to other populations.
OBJECTIVE: To report our recent experience with prenatal detection of significant cardiovascular malformations (CVMs) in Nevada's state-wide maternal population receiving prenatal care. METHODS: We queried our databases for those with significant CVMs diagnosed pre- or postnatally between May 1, 2021, and April 30, 2024. We defined CVMs as those that required, would have required, or will likely require a therapeutic procedure in the first 12 months. Additionally, we included those with atrioventricular and ventriculoarterial discordance and left isomeric situs, both unaccompanied by additional CVMs, and congenital complete heart block. We defined routine prenatal care as obstetric care, which included at least one fetal anatomical survey ultrasound. RESULTS: We identified 390 cases of significant CVMs. Of the 390 cases, 359 (92%) had prenatal care over the three-year observation period, with prenatal detection rates for the three 12-month intervals: 76% (87/115), 87% (94/108), and 95% (129/136) respectively (p < 0.001 by chi-square). A total of 310 prenatal diagnoses were made from comprehensive fetal echocardiograms performed on 8397 pregnant women at maternal-fetal-medicine centers. CONCLUSION: To our knowledge, these results represent the highest prenatal detection rate for significant CVMs, in a state-wide maternal population in the United States.
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Evans et al. (2024) conducted an observational in Significant cardiovascular malformations (n=390). Routine prenatal care and comprehensive fetal echocardiography was evaluated on Prenatal detection rate of significant cardiovascular malformations across three 12-month intervals (p=<0.001). Comprehensive fetal echocardiography and routine prenatal care in Nevada achieved a 95% prenatal detection rate for significant cardiovascular malformations in the final year of observation.
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