Key result
In patients with type 2 diabetes and diabetic nephropathy, a mean carotid intima-media thickness ≥1.0 mm was associated with a significantly faster yearly decline in eGFR (-7.1 vs -4.4 mL/min/yr).
Why the study?
Is carotid intima-media thickness associated with the progression of diabetic nephropathy in patients with type 2 diabetes?
Observational (n=354)
No
Is carotid intima-media thickness associated with the progression of diabetic nephropathy in patients with type 2 diabetes?
Absolute Event Rate: -7.1% vs -4.4%
p-value: p=0.026
Carotid intima-media thickness measured by ultrasound is an independent predictor of renal function decline in patients with type 2 diabetes and nephropathy.
May inform risk stratification in T2D nephropathy; hypothesis-generating pending prospective validation.
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Cho et al. (2011) conducted an observational in Type 2 diabetes with diabetic nephropathy (n=354). Carotid intima-media thickness (IMT) ≥1.0 mm vs. Carotid IMT <1.0 mm was evaluated on Yearly change of eGFR (mL/min/yr) (p=0.026). In patients with type 2 diabetes and diabetic nephropathy, a mean carotid intima-media thickness ≥1.0 mm was associated with a significantly faster yearly decline in eGFR (-7.1 vs -4.4 mL/min/yr).
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