Aortic Valve Dysfunction and Aortic Dilation in Adults with Coarctation of the Aorta
Key result
Bicuspid aortic valve in adults with coarctation of the aorta was associated with higher rates of moderate or severe ascending aortic dilation compared to those without BAV (19.5% vs 0%; P<0.001).
Population
216 adults with coarctation of the aorta (repaired or unrepaired), median age 28.3 years, 56.0% male.
Design
Cohort
Authors
Discussion
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Member takes
Implication
May warrant closer aortic surveillance in coarctation with BAV; leaves open progression risk and intervention thresholds.
Study Design
Type
Observational (n=216)
Multicenter
No
Structured PICO
P
Population
216 adults with coarctation of the aorta (repaired or unrepaired), median age 28.3 years, 56.0% male.
O
Outcome
Prevalence of aortic valve dysfunction, aortic dilation, and aortic valve and ascending aortic intervention
In adults with coarctation of the aorta, aortic dilation is highly prevalent, particularly in the ascending aorta among those with a bicuspid aortic valve, despite a low rate of significant aortic valve dysfunction.
Cite This Study
Clair et al. (2013) conducted an observational in Coarctation of the aorta (CoA) (n=216). Bicuspid aortic valve in adults with coarctation of the aorta was associated with higher rates of moderate or severe ascending aortic dilation compared to those without BAV (19.5% vs 0%; P<0.001).