Key result
Arterial stiffness and wave reflections independently predict elderly CV events via augmented central pulse pressure.
Why the study?
Arterial stiffness and wave reflections predict cardiovascular events in elderly hypertensive patients, and recent concepts like Early and Supernormal Vascular Ageing help identify modifiable determinants to limit target organ damage.
Arterial stiffness is a key determinant of cardiovascular risk in elderly hypertensives, and understanding concepts like Early Vascular Ageing can help limit target organ damage.
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Supports stiffness assessment for risk stratification in elderly hypertensives; leaves open whether targeting early vascular ageing improves outcomes.
Laurent et al. (2020) conducted a review in Hypertension and Arterial Stiffness. Arterial stiffness and wave reflections increase with age and hypertension, leading to augmented central pulse pressure and target organ damage, and serve as independent predictors of cardiovascular events in the elderly.
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