Population
Anesthetized, paralyzed, and ventilated cats
Comparison
Respiratory challenges including: 1) cessation… vs Control conditions (spontaneous activity)
Design
Preclinical
Authors
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Animal findings in anesthetized models warrant caution before clinical translation; extends basic mechanisms of cerebellar respiratory integration.
Cerebellar respiratory-related neurons respond to respiratory inputs from CO2 chemo- and pulmonary mechanoreceptors in the absence of skeletal muscle contraction.
Xu et al. (1997) studied this question.
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