December 15, 1996American Journal of Epidemiology
Passive Smoking and Plasma Fibrinogen Concentrations
Why the study?
Does passive smoking increase plasma fibrinogen concentrations in women aged 45-74 years?
Population
1,780 Japanese women aged 45-74 years residing in Kyowa town, Ibaraki-ken, Japan
Comparison
Passive smoking exposure vs Unexposed to passive smoking in either location
Design
Cross-sectional
Authors
Discussion
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Implication
May explain part of passive smoking's CHD risk via fibrinogen in women; hypothesis-generating and needs prospective studies.
Structured PICO
Does passive smoking increase plasma fibrinogen concentrations in women aged 45-74 years?
P
Population
1,780 Japanese women aged 45-74 years residing in Kyowa town, Ibaraki-ken, Japan
I
Intervention
Passive smoking exposure (outside the home, or both in and outside the home)
C
Comparator
Unexposed to passive smoking in either location (n=524)
O
Outcome
Plasma fibrinogen concentrationssurrogate
Passive smoking outside the home or both in and outside the home is associated with significantly higher plasma fibrinogen concentrations in women, suggesting a potential mechanism for increased coronary heart disease risk.
Cite This Study
Iso et al. (1996) studied this question.