Key result
White individuals on dialysis had a significantly higher incidence of new atherosclerotic cardiovascular disease compared with Black individuals (146.9 vs 118.7 per 1000 person-years; HR 1.35, 95% CI 1.18-1.55).
Why the study?
Does White race compared to Black race increase the incidence of new and recurrent ASCVD events in patients with ESRD on dialysis?
Population
16,103 people who had ESRD and were enrolled in the United Renal Data System from 1993 to 1996
Comparison
White race (exposure) vs Black race
Design
Cohort
Authors
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Suggests closer ASCVD surveillance for White dialysis patients; observational data leaves open mechanisms and targeted interventions.
Cohort (n=16,103)
Yes
Does White race compared to Black race increase the incidence of new and recurrent ASCVD events in patients with ESRD on dialysis?
Effect estimate: HR 1.35 (95% CI 1.18 to 1.55)
Absolute Event Rate: 146.9% vs 118.7%
White patients on dialysis have a significantly higher risk of both new and recurrent ASCVD events compared to Black patients, a disparity not explained by traditional or dialysis-related risk factors.
Parekh et al. (2005) conducted a cohort in End-stage renal disease (ESRD) on dialysis (n=16,103). White race vs. Black race was evaluated on Incidence of new atherosclerotic CVD (ASCVD) events in people without ASCVD at baseline (HR 1.35, 95% CI 1.18 to 1.55). White individuals on dialysis had a significantly higher incidence of new atherosclerotic cardiovascular disease compared with Black individuals (146.9 vs 118.7 per 1000 person-years; HR 1.35, 95% CI 1.18-1.55).
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